Diversity among Multidrug-Resistant Enterococci

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Diversity among multidrug-resistant enterococci.

Enterococci are associated with both community- and hospital-acquired infections. Even though they do not cause severe systemic inflammatory responses, such as septic shock, enterococci present a therapeutic challenge because of their resistance to a vast array of antimicrobial drugs, including cell-wall active agents, all commercially available aminoglycosides, penicillin and ampicillin, and v...

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Multidrug-Resistant Enterococci Lack CRISPR-cas

Clustered, regularly interspaced short palindromic repeats (CRISPR) provide bacteria and archaea with sequence-specific, acquired defense against plasmids and phage. Because mobile elements constitute up to 25% of the genome of multidrug-resistant (MDR) enterococci, it was of interest to examine the codistribution of CRISPR and acquired antibiotic resistance in enterococcal lineages. A database...

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A Novel Way of Treating Multidrug-resistant Enterococci

CONTEXT Daptomycin is the only antibiotic available with in vitro bactericidal activity against vancomycin-resistant enterococci (VRE). Its increased use has resulted in cases of decreased daptomycin efficacy. Recent in vitro studies have shown effective use of beta (β)-lactam and daptomycin antibiotics, as a combination therapy, in the treatment of VRE. We describe a case of effective treatmen...

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Recurrence of Multidrug-Resistant Enterococci in a Neutropenic Patient.

Over the past 20 years, multidrug-resistant enterococci (MDRE) have emerged as a leading cause of nosocomial infections. Its importance stems not only from its increasing incidence among high-risk hospital populations, but also from the lack of established effective therapy in eradicating the pathogen. There is increasing awareness of MDRE reservoirs in settings such as oncology wards, intensiv...

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Characterization of multidrug-resistant diabetic foot ulcer enterococci.

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ژورنال

عنوان ژورنال: Emerging Infectious Diseases

سال: 1998

ISSN: 1080-6040

DOI: 10.3201/eid0401.980106